A new mechanism of thermal sensitivity for rapid drug release and low systemic toxicity in hyperthermia and thermal ablation temperature ranges

• Main Authors: Dabbagh, Ali, Abdullah, Basri Johan Jeet, Abu Kasim, Noor Hayaty, Abdullah, Hadijah, Abd Shukor, Mohd Hamdi
• Format: Article
• Language: English
• Published: Taylor & Francis 2015
• Subjects: RK Dentistry
• Online Access: http://eprints.um.edu.my/14011/1/A_new_mechanism_of_thermal_sensitivity_for_rapid_drug_release_and_low_systemic_toxicity_in_hyperthermia_and_thermal_ablation_temperature_ranges.pdf; http://eprints.um.edu.my/14011/; https://doi.org/10.3109/02656736.2015.1006268

Purpose: The aim of this paper was to introduce a new mechanism of thermal sensitivity in nanocarriers that results in a relatively low drug release at physiological temperature and rapid release of the encapsulated drug at hyperthermia and thermal ablation temperature range (4060 degrees C). Materi...