A prospective study on the natural course of low-grade squamous intraepithelial lesions and the presence of HPV16 E2-, E6- and E7-specific T-cell responses

• Main Authors: Woo, Y.L., van den Hende, M., Sterling, J.C., Coleman, N., Crawford, R.A.F., Kwappenberg, K.M.C., Stanley, M.A., Van Der Burg, S.H.
• Format: Article
• Published: John Wiley & Sons 2010
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/12855/; http://onlinelibrary.wiley.com/doi/10.1002/ijc.24804/abstract; http://dx.doi.org/10.1002/ijc.24804

This study investigates the clinical course of low grade squamous intraepithelial lesions (LSIL), HPV status and HPV16-specific immune response in a large prospective study of 125 women with LSIL followed cytologically, virologically and histologically. Women with low-grade abnormal smears were recr...