Symptomatic anaemia 17 years after double valve replacement

A 40-year-old Malay woman presented with increasing lethargy, palpitation and shortness of breath, 17 years after a mitral and aortic valve replacement. A Starr-Edwards prosthetic valve replaced the mitral valve, and a Bjork-Shiley prosthetic valve replaced the aortic valve. Biochemical parameters d...

Full description

Saved in:
Bibliographic Details
Main Authors: Wong, M.H., Chee, K.H., Azman, W.
Format: Article
Published: Stamford Publishing Pte Ltd / Singapore Medical Association 2009
Subjects:
Online Access:http://eprints.um.edu.my/1176/
http://www.ncbi.nlm.nih.gov/pubmed/19907876
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.um.eprints.1176
record_format eprints
spelling my.um.eprints.11762019-01-14T01:37:08Z http://eprints.um.edu.my/1176/ Symptomatic anaemia 17 years after double valve replacement Wong, M.H. Chee, K.H. Azman, W. R Medicine A 40-year-old Malay woman presented with increasing lethargy, palpitation and shortness of breath, 17 years after a mitral and aortic valve replacement. A Starr-Edwards prosthetic valve replaced the mitral valve, and a Bjork-Shiley prosthetic valve replaced the aortic valve. Biochemical parameters demonstrated intravascular haemolysis, as evidenced by haemoglobin 7.8 g/dL, reticulocyte count 8.4%, lactate dehydrogenase 2,057 IU/L and low haptoglobulin levels (less than 6 mg/dL). Transoesophageal echocardiography revealed a paravalvular leakage over the mitral valve. The haemoglobin levels remained persistently low despite frequent blood transfusions. She successfully underwent a second mitral valve replacement. Her anaemia resolved subsequently. Stamford Publishing Pte Ltd / Singapore Medical Association 2009-10 Article PeerReviewed Wong, M.H. and Chee, K.H. and Azman, W. (2009) Symptomatic anaemia 17 years after double valve replacement. Singapore Medical Journal, 50 (10). pp. 362-4. ISSN 0037-5675 http://www.ncbi.nlm.nih.gov/pubmed/19907876 19907876
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
topic R Medicine
spellingShingle R Medicine
Wong, M.H.
Chee, K.H.
Azman, W.
Symptomatic anaemia 17 years after double valve replacement
description A 40-year-old Malay woman presented with increasing lethargy, palpitation and shortness of breath, 17 years after a mitral and aortic valve replacement. A Starr-Edwards prosthetic valve replaced the mitral valve, and a Bjork-Shiley prosthetic valve replaced the aortic valve. Biochemical parameters demonstrated intravascular haemolysis, as evidenced by haemoglobin 7.8 g/dL, reticulocyte count 8.4%, lactate dehydrogenase 2,057 IU/L and low haptoglobulin levels (less than 6 mg/dL). Transoesophageal echocardiography revealed a paravalvular leakage over the mitral valve. The haemoglobin levels remained persistently low despite frequent blood transfusions. She successfully underwent a second mitral valve replacement. Her anaemia resolved subsequently.
format Article
author Wong, M.H.
Chee, K.H.
Azman, W.
author_facet Wong, M.H.
Chee, K.H.
Azman, W.
author_sort Wong, M.H.
title Symptomatic anaemia 17 years after double valve replacement
title_short Symptomatic anaemia 17 years after double valve replacement
title_full Symptomatic anaemia 17 years after double valve replacement
title_fullStr Symptomatic anaemia 17 years after double valve replacement
title_full_unstemmed Symptomatic anaemia 17 years after double valve replacement
title_sort symptomatic anaemia 17 years after double valve replacement
publisher Stamford Publishing Pte Ltd / Singapore Medical Association
publishDate 2009
url http://eprints.um.edu.my/1176/
http://www.ncbi.nlm.nih.gov/pubmed/19907876
_version_ 1643686685488185344
score 13.160551