Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia

There is an increasing trend for Shigella isolates worldwide to be resistant to commonly prescribed antibiotics. The species distribution and antibiotic resistance of Shigella species isolated from children in Kuala Lumpur, Malaysia from 1978 to 1997 was reviewed. Three hundred and eighty six isolat...

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Main Authors: Lee, W.S., Puthucheary, S.D.
Format: Article
Language:English
Published: 2003
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Online Access:http://eprints.um.edu.my/10920/1/Species_distribution_and_antibiotic_resistance.pdf
http://eprints.um.edu.my/10920/
http://www.e-mjm.org/2003/v58n2/Antibiotic_Resistance_Shigella.pdf
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spelling my.um.eprints.109202014-07-14T00:21:39Z http://eprints.um.edu.my/10920/ Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia Lee, W.S. Puthucheary, S.D. R Medicine RJ Pediatrics There is an increasing trend for Shigella isolates worldwide to be resistant to commonly prescribed antibiotics. The species distribution and antibiotic resistance of Shigella species isolated from children in Kuala Lumpur, Malaysia from 1978 to 1997 was reviewed. Three hundred and eighty six isolates were positive for Shigella species, representing 1.4 (95 CI: 1.3-1.6) of the 26320 total stool specimens and 13 (95 CI: 11.8-14.2) of 2986 isolates positive for bacterial pathogens. Shigella flexneri, constituting 74 of all isolates in the first five years of the study, decreased by 40 during the last five years (95 CI of decrease: 22.1-57.9), p-value < 0.0001) to 34. There was a significant reduction (chi2 for linear trend = 77.6, p-value < 0.001) in the number of Shigella isolates as a percentage of total stool isolates obtained. 58 of the 241 isolates tested for antibiotic sensitivity were resistant to at least one antibiotic, and 42 wEre multi-resistant to three or more antibiotics. Shigella species was not a common pathogen among children admitted with diarrhoea in Kuala Lumpur, and was more likely to be resistant to commonly prescribed antibiotics. 2003 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10920/1/Species_distribution_and_antibiotic_resistance.pdf Lee, W.S. and Puthucheary, S.D. (2003) Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia. Medical Journal of Malaysia, 58 (2). pp. 262-267. ISSN 0300-5283 http://www.e-mjm.org/2003/v58n2/Antibiotic_Resistance_Shigella.pdf
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic R Medicine
RJ Pediatrics
spellingShingle R Medicine
RJ Pediatrics
Lee, W.S.
Puthucheary, S.D.
Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia
description There is an increasing trend for Shigella isolates worldwide to be resistant to commonly prescribed antibiotics. The species distribution and antibiotic resistance of Shigella species isolated from children in Kuala Lumpur, Malaysia from 1978 to 1997 was reviewed. Three hundred and eighty six isolates were positive for Shigella species, representing 1.4 (95 CI: 1.3-1.6) of the 26320 total stool specimens and 13 (95 CI: 11.8-14.2) of 2986 isolates positive for bacterial pathogens. Shigella flexneri, constituting 74 of all isolates in the first five years of the study, decreased by 40 during the last five years (95 CI of decrease: 22.1-57.9), p-value < 0.0001) to 34. There was a significant reduction (chi2 for linear trend = 77.6, p-value < 0.001) in the number of Shigella isolates as a percentage of total stool isolates obtained. 58 of the 241 isolates tested for antibiotic sensitivity were resistant to at least one antibiotic, and 42 wEre multi-resistant to three or more antibiotics. Shigella species was not a common pathogen among children admitted with diarrhoea in Kuala Lumpur, and was more likely to be resistant to commonly prescribed antibiotics.
format Article
author Lee, W.S.
Puthucheary, S.D.
author_facet Lee, W.S.
Puthucheary, S.D.
author_sort Lee, W.S.
title Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia
title_short Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia
title_full Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia
title_fullStr Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia
title_full_unstemmed Species distribution and antibiotic resistance of Shigella isolates in an urban community in Malaysia
title_sort species distribution and antibiotic resistance of shigella isolates in an urban community in malaysia
publishDate 2003
url http://eprints.um.edu.my/10920/1/Species_distribution_and_antibiotic_resistance.pdf
http://eprints.um.edu.my/10920/
http://www.e-mjm.org/2003/v58n2/Antibiotic_Resistance_Shigella.pdf
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score 13.188404