Regular paracetamol in severe dengue: a lethal combination?

An eight-month-old female infant with severe dengue disease, who was repeatedly given therapeutic paracetamol for severe dengue, developed fulminant liver failure with encephalopathy, gastrointestinal haemorrhage and severe coagulopathy. She responded to supportive measures and N-acetylcysteine infu...

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Main Authors: Gan, C.S., Chong, S.Y., Lum, L.C.S., Lee, W.S.
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:http://eprints.um.edu.my/10877/1/Regular_paracetamol_in_severe_dengue.pdf
http://eprints.um.edu.my/10877/
http://www.sma.org.sg/Publications/articles.aspx?ID=4BD31167-B8D9-49CA-A2FD-C2440D46AAFC
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spelling my.um.eprints.108772014-07-13T06:35:50Z http://eprints.um.edu.my/10877/ Regular paracetamol in severe dengue: a lethal combination? Gan, C.S. Chong, S.Y. Lum, L.C.S. Lee, W.S. R Medicine RJ Pediatrics An eight-month-old female infant with severe dengue disease, who was repeatedly given therapeutic paracetamol for severe dengue, developed fulminant liver failure with encephalopathy, gastrointestinal haemorrhage and severe coagulopathy. She responded to supportive measures and N-acetylcysteine infusion. This case highlights the potential danger of administering repeated therapeutic doses of paracetamol in childhood severe dengue disease with hepatitis. 2013 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10877/1/Regular_paracetamol_in_severe_dengue.pdf Gan, C.S. and Chong, S.Y. and Lum, L.C.S. and Lee, W.S. (2013) Regular paracetamol in severe dengue: a lethal combination? Singapore Medical Journal, 54 (2). E35-E37. ISSN 0037-5675 http://www.sma.org.sg/Publications/articles.aspx?ID=4BD31167-B8D9-49CA-A2FD-C2440D46AAFC 10.11622/smedj.2013037
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic R Medicine
RJ Pediatrics
spellingShingle R Medicine
RJ Pediatrics
Gan, C.S.
Chong, S.Y.
Lum, L.C.S.
Lee, W.S.
Regular paracetamol in severe dengue: a lethal combination?
description An eight-month-old female infant with severe dengue disease, who was repeatedly given therapeutic paracetamol for severe dengue, developed fulminant liver failure with encephalopathy, gastrointestinal haemorrhage and severe coagulopathy. She responded to supportive measures and N-acetylcysteine infusion. This case highlights the potential danger of administering repeated therapeutic doses of paracetamol in childhood severe dengue disease with hepatitis.
format Article
author Gan, C.S.
Chong, S.Y.
Lum, L.C.S.
Lee, W.S.
author_facet Gan, C.S.
Chong, S.Y.
Lum, L.C.S.
Lee, W.S.
author_sort Gan, C.S.
title Regular paracetamol in severe dengue: a lethal combination?
title_short Regular paracetamol in severe dengue: a lethal combination?
title_full Regular paracetamol in severe dengue: a lethal combination?
title_fullStr Regular paracetamol in severe dengue: a lethal combination?
title_full_unstemmed Regular paracetamol in severe dengue: a lethal combination?
title_sort regular paracetamol in severe dengue: a lethal combination?
publishDate 2013
url http://eprints.um.edu.my/10877/1/Regular_paracetamol_in_severe_dengue.pdf
http://eprints.um.edu.my/10877/
http://www.sma.org.sg/Publications/articles.aspx?ID=4BD31167-B8D9-49CA-A2FD-C2440D46AAFC
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score 13.18916