Chemopreventive evaluation of a Schiff base derived copper (II) complex against Azoxymethane-induced colorectal cancer in rats

• Main Authors: Hajrezaie, M., Hassandarvish, P., Moghadamtousi, S.Z., Gwaram, N.S., Golbabapour, S., NajiHussien, A., Almagrami, A.M., Zahedifard, M., Rouhollahi, E., Karimian, H., Fani, F., Kamalidehghan, B., Majid, N.A., Ali, H.M., Abdulla, M.A.
• Format: Article
• Language: English
• Published: Public Library of Science 2014
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/10512/1/Chemopreventive_Evaluation_of_a_Schiff_Base_Derived.pdf; http://eprints.um.edu.my/10512/

Background: Based on the potential of Schiff base compounds to act as sources for the development of cancer chemotherapeutic agents, this in vivo study was performed to investigate the inhibitory properties of the synthetic Schiff base compound Cu(BrHAP)2 on colonic aberrant crypt foci (ACF). Metho...