Vasorelaxant effect of isoquinoline derivatives from two species of Popowia perakensis and Phaeanthus crassipetalus on rat aortic artery

• Main Authors: Awang, K., Zaima, K., Takeyama, Y., Koga, I., Saito, A., Tamamoto, H., Syed Abd. Azziz, S.S., Mukhtar, M.R., Hadi, A.H., Morita, H.
• Format: Article
• Language: English
• Published: Springer Verlag 2012
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/10486/1/Vasorelaxant_effect_of_isoquinoline_derivatives_from_two_species_of_Popowia_perakensis_and_Phaeanthus_crassipetalus_on_rat_aortic_artery.pdf; http://eprints.um.edu.my/10486/

Five bisbenzyl isoquinolines (1-5), three benzyl isoquinolines (6-8), four isoquinoline alkaloids (9-12), and two unclassified compounds (13 and 14) from Popowia perakensis and Phaeanthus crassipetalus were evaluated for their vasorelaxant effect on rat aortic arteries. In aortic rings pre-contracte...