Enyne- and enediyne-y-lactonefrso m the bark of Meiogyne cylindrocarpa
The chemical investigation ofthe EtOAc extract ofthe bark ofMeiogrne qilindrocarpa led to the isolation of two enyne- and five enediynel-lactones, sapranthins A-G (1 -7), of which six were new. They were identified by mass spectrometry,extensive one- and two-dimensional NMR spectroscopya nd through...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2012
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| Subjects: | |
| Online Access: | http://eprints.um.edu.my/10450/1/Enyne-_and_enediyne-y-lactonefrso_m_the_bark_of_Meiogyne____cylindrocarpa.pdf http://eprints.um.edu.my/10450/ |
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| Summary: | The chemical investigation ofthe EtOAc extract ofthe bark ofMeiogrne qilindrocarpa led to the isolation of two enyne- and five enediynel-lactones, sapranthins A-G (1 -7), of which six were new. They were identified by mass spectrometry,extensive one- and two-dimensional NMR spectroscopya nd through comparison with data reported in the Iiterature.S apranthinsB , C and E (2,3 and 5, respectively showed a weak cytotoxic activity on L1210 with lC50 values comprised between 8.1 and 18.0 µM. |
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