Strychnan and secoangustilobine A type alkaloids from alstonia spatulata. Revision of the C-20 configuration of scholaricine

• Main Authors: Kam, T.S., Tan, S.J., Low, Y.Y., Choo, Y.M., Abdullah, Z., Etoh, T., Hayashi, M., Komiyama, K.
• Format: Article
• Language: English
• Published: American Chemical Society and American Society of Pharmacognosy 2010
• Subjects: QD Chemistry
• Online Access: http://eprints.um.edu.my/10400/1/Strychnan_and_Secoangustilobine_A_Type_Alkaloids_from_Alstonia_spatulata._Revision_of_the_C-20_Configuration_of_Scholaricine.pdf; http://eprints.um.edu.my/10400/

A total of 25 alkaloids were isolated from the leaf and stem-bark extracts of Alstonia spatulata, of which five are new alkaloids of the strychnan type (alstolucines A-E, 1-5)and the other, a new alkaloid of the secoangustilobine A type(alstolobine A, 6). The structures of these alkaloids were estab...