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Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba

A total of 20 alkaloids were isolated from the leaf and stem-bark extracts of Alstonia angustiloba, of which two are hitherto unknown. One is an alkaloid of the angustilobine type (angustilobine C), while the other is a bisindole alkaloid angustiphylline, derived from the union of uleine and secoval...

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Main Authors: Kam, T.S., Ku, W.F., Tan, S.J., Low, Y.Y., Komiyama, K.
Format: Article
Language:English
Published: Elsevier 2011
Subjects:
QD Chemistry
Online Access:http://eprints.um.edu.my/10391/1/Angustilobine_and_andranginine_type_indole_alkaloids_and_an.pdf
http://eprints.um.edu.my/10391/
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spelling my.um.eprints.103912014-10-15T01:52:21Z http://eprints.um.edu.my/10391/ Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba Kam, T.S. Ku, W.F. Tan, S.J. Low, Y.Y. Komiyama, K. QD Chemistry A total of 20 alkaloids were isolated from the leaf and stem-bark extracts of Alstonia angustiloba, of which two are hitherto unknown. One is an alkaloid of the angustilobine type (angustilobine C), while the other is a bisindole alkaloid angustiphylline, derived from the union of uleine and secovallesamine moieties. The structures of these alkaloids were established using NMR and MS analysis. Angustilobine C showed moderate cytotoxicity towards KB cells. Elsevier 2011 Article PeerReviewed application/pdf en http://eprints.um.edu.my/10391/1/Angustilobine_and_andranginine_type_indole_alkaloids_and_an.pdf Kam, T.S. and Ku, W.F. and Tan, S.J. and Low, Y.Y. and Komiyama, K. (2011) Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba. Phytochemistry, 72. pp. 2212-2218. ISSN 0031-9422 doi:10.1016/j.phytochem.2011.08.001
institution Universiti Malaya
building UM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Malaya
content_source UM Research Repository
url_provider http://eprints.um.edu.my/
language English
topic QD Chemistry
spellingShingle QD Chemistry
Kam, T.S.
Ku, W.F.
Tan, S.J.
Low, Y.Y.
Komiyama, K.
Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba
description A total of 20 alkaloids were isolated from the leaf and stem-bark extracts of Alstonia angustiloba, of which two are hitherto unknown. One is an alkaloid of the angustilobine type (angustilobine C), while the other is a bisindole alkaloid angustiphylline, derived from the union of uleine and secovallesamine moieties. The structures of these alkaloids were established using NMR and MS analysis. Angustilobine C showed moderate cytotoxicity towards KB cells.
format Article
author Kam, T.S.
Ku, W.F.
Tan, S.J.
Low, Y.Y.
Komiyama, K.
author_facet Kam, T.S.
Ku, W.F.
Tan, S.J.
Low, Y.Y.
Komiyama, K.
author_sort Kam, T.S.
title Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba
title_short Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba
title_full Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba
title_fullStr Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba
title_full_unstemmed Angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from Alstonia angustiloba
title_sort angustilobine and andranginine type indole alkaloids and an uleine–secovallesamine bisindole alkaloid from alstonia angustiloba
publisher Elsevier
publishDate 2011
url http://eprints.um.edu.my/10391/1/Angustilobine_and_andranginine_type_indole_alkaloids_and_an.pdf
http://eprints.um.edu.my/10391/
_version_ 1643688787631407104
score 13.214268

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