Lapatinib induced-changes in Caco-2 intestinal monolayer via ErbB1 inhibition / Raja Nur Firzanah Syaza Raja Sharin

Lapatinib (LAP) is an orally administered dual ErbBl and ErbB2 tyrosine kinase inhibitor for ErbB2-positive breast tumours, but is associated with diarrhoea. Incidence of lapatinib-induced diarrhoea (LID) is as high as 58-78% in treated patients. Although short-term diarrhoea is tolerable, prolonged...

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Bibliographic Details
Main Author: Raja Sharin, Raja Nur Firzanah Syaza
Format: Thesis
Language:English
Published: 2023
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/91425/1/91425.pdf
https://ir.uitm.edu.my/id/eprint/91425/
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