Cover Image

In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin

Wounds and their treatment significantly strain the healthcare system in terms of cost, time, and energy expended. The productivity and quality of life setbacks are incalculable. Herbal remedies are widely used in complementary and alternative medicine worldwide. Rhodomyrtus tomentosa leaves or know...

Full description

Saved in:
Bibliographic Details
Main Author: Kamarudin, Evana
Format: Thesis
Language:English
Published: 2023
Online Access:https://ir.uitm.edu.my/id/eprint/89510/1/89510.pdf
https://ir.uitm.edu.my/id/eprint/89510/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.uitm.ir.89510
record_format eprints
spelling my.uitm.ir.895102024-01-16T03:10:04Z https://ir.uitm.edu.my/id/eprint/89510/ In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin Kamarudin, Evana Wounds and their treatment significantly strain the healthcare system in terms of cost, time, and energy expended. The productivity and quality of life setbacks are incalculable. Herbal remedies are widely used in complementary and alternative medicine worldwide. Rhodomyrtus tomentosa leaves or known as "Kemunting", which are traditionally claimed to treat wounds, have not been proven scientifically. This research aimed to elucidate the mechanism of action of rhodomyrtone, Fraction 5-ethylacetate (F5-EA) of R. tomentosa crude ethanolic extract (SERT) in enhancing the wound healing through Wnt/fi-catenin pathway. The first part of this study wasconducted to profile SERT, identify, and quantify rhodomyrtone in liquid-liquidextraction (LLE) Fractions 1 - 6 of the SERT by conducting liquid chromatography -mass spectrophotometry (LCMS). Free radical scavenging activity (DPPH) was used to assess the antioxidant activity of SERT and LLE Fractions 1-6. 2023 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/89510/1/89510.pdf In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin. (2023) PhD thesis, thesis, Universiti Teknologi MARA (UiTM). <http://terminalib.uitm.edu.my/89510.pdf>
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
description Wounds and their treatment significantly strain the healthcare system in terms of cost, time, and energy expended. The productivity and quality of life setbacks are incalculable. Herbal remedies are widely used in complementary and alternative medicine worldwide. Rhodomyrtus tomentosa leaves or known as "Kemunting", which are traditionally claimed to treat wounds, have not been proven scientifically. This research aimed to elucidate the mechanism of action of rhodomyrtone, Fraction 5-ethylacetate (F5-EA) of R. tomentosa crude ethanolic extract (SERT) in enhancing the wound healing through Wnt/fi-catenin pathway. The first part of this study wasconducted to profile SERT, identify, and quantify rhodomyrtone in liquid-liquidextraction (LLE) Fractions 1 - 6 of the SERT by conducting liquid chromatography -mass spectrophotometry (LCMS). Free radical scavenging activity (DPPH) was used to assess the antioxidant activity of SERT and LLE Fractions 1-6.
format Thesis
author Kamarudin, Evana
spellingShingle Kamarudin, Evana
In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin
author_facet Kamarudin, Evana
author_sort Kamarudin, Evana
title In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin
title_short In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin
title_full In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin
title_fullStr In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin
title_full_unstemmed In vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / Evana Kamarudin
title_sort in vitro wound healing potential and the identification of related bioactive compound(s) from rhodomyrtus tomentosa (aiton) hassk / evana kamarudin
publishDate 2023
url https://ir.uitm.edu.my/id/eprint/89510/1/89510.pdf
https://ir.uitm.edu.my/id/eprint/89510/
_version_ 1789429282667233280
score 13.2014675

Similar Items