Antioxidant and antibacterial properties of aloe vera extract against e. Coli and s. Aureus bacteria / Siti Hawarul Ain Kamarudin

• Main Author: Kamarudin, Siti Hawarul Ain
• Format: Student Project
• Language: English
• Published: 2023
• Subjects: Bioactive compounds
• Online Access: https://ir.uitm.edu.my/id/eprint/87974/1/87974.pdf; https://ir.uitm.edu.my/id/eprint/87974/

Pathogenic bacterial can give a rise to many affections’ disease and these microorganisms’ property of being able to develop drug resistance may cause serious global threat to the welfare of people, animals, and the environment Aloe vera has been used as alternative to develop new antibiotics to to treat and cure a number of bacterial infections. Aloe vera also contains a compound that has an antioxidant and antibacterial effect against Staphylococcus aureus and Escherichia coli. An experiment has been conducted to determine the antibacterial activity of an ethanolic and methanolic extract of Aloe vera in five different concentrations, which are 5%, 25%, 50%, 80% and 100% by using disc diffusion assays. While antioxidant activity of the ethanolic and methanolic aloe vera extract is determine by using DPPH methods. The results show that the ethanolic extract of aloe vera can inhibit the growth of the gram-positive bacteria S. aureus at all concentrations. However, ethanolic extract can only inhibit the growth of E. coli at concentrations 80% and 100%. Methanolic extract shows inhibitory effects on S. aureus but limited inhibition zone for E. coli. In conclusion, ethanolic and methanolic extracts of aloe vera are have a potential as antibacterial against S. aureus but less effect on E.coli. Ascorbic acid shows highest antioxidant activity compared to Ethanolicextract and Methanolic extract of Aloe Vera. However, there were only slightlydifferent of the value between both extract and ascorbic acid.