The anti-cataract effect of topical magnesium taurate on rats fed with 30% galactose diet / Nur Farhana Ahmad Fisol

Cataract, a leading cause of blindness, accounts for nearly half ( 47.8%) of all cases of blindness. There were numerous studies done on magnesium and taurine independently that suggest both magnesium and taurine could delay the development of cataract in rats. Thus, the combination of both as magne...

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Bibliographic Details
Main Author: Ahmad Fisol, Nur Farhana
Format: Thesis
Language:English
Published: 2012
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/72166/1/72166.pdf
https://ir.uitm.edu.my/id/eprint/72166/
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Summary:Cataract, a leading cause of blindness, accounts for nearly half ( 47.8%) of all cases of blindness. There were numerous studies done on magnesium and taurine independently that suggest both magnesium and taurine could delay the development of cataract in rats. Thus, the combination of both as magnesium taurate preparation should be prudent to delay the progression of galactose induced cataract in rats. This study was done to evaluate the effect of topical magnesium taurate on the development and progression of galactose-induced cataract in rats. Forty five Sprague-Dawley rats, weighed around 80-l00g, of either sex were randomly divided into three groups; (!)normal diet (ND), (2) 30% galactose diet (GD) and (3) 30% galactose diet with topical magnesium taurate treatment (GD+MgT).