Development of a PCR test for detection of warfarin resistance based on the polymorphism of VKORC1 genes / Mohd Hafiz Mohd Saif

• Main Author: Mohd Saif, Mohd Hafiz
• Format: Thesis
• Language: English
• Published: 2012
• Subjects: Medical education. Medical schools. Research; Drugs and their actions
• Online Access: https://ir.uitm.edu.my/id/eprint/65553/1/65553.pdf; https://ir.uitm.edu.my/id/eprint/65553/

VKORC1 gene plays important role in coding for Vitamin K Epoxide Reductase for determining the warfarin resistance. Screening of polymorphism of VKORC1 before starting drug therapy as different patient will act differently to the warfarin therapy. The aim of this study is to develop and validate a P...