Molecular docking study of naturally derived β-mangostin with antiapoptotic Bcl-2 proteins toward oral cancer treatment / Mohamad Zakkirun Abdullah ... [et al.]

• Main Authors: Abdullah, Mohamad Zakkirun, Bakar, Latifah Munirah, Arief Ichwan, Solachuddin Jauhari, Othman, Noratikah, Taher, Muhammad
• Format: Article
• Language: English
• Published: Universiti Teknologi MARA Cawangan Pulau Pinang 2022
• Subjects: Cancer; Research. Experimentation
• Online Access: https://ir.uitm.edu.my/id/eprint/62610/1/62610.pdf; https://ir.uitm.edu.my/id/eprint/62610/; https://uppp.uitm.edu.my/

Targeting the apoptosis-inducing pathway has drawn much attention in searching for a novel anticancer drug. Bcl-2 is the most studied antiapoptotic protein, recognised in aiding in cell survival and overexpressed in most cancer cells resulting in cancer resistance toward conventional treatment. The...