Xanthones from fruit hulls of garcinia mangostana / Nur Adrini Abdullah

• Main Author: Abdullah, Nur Adrini
• Format: Student Project
• Language: English
• Published: 2019
• Subjects: Extraction (Chemistry); Analytical chemistry; Medicinal plants (Culture only)
• Online Access: http://ir.uitm.edu.my/id/eprint/44889/1/44889.pdf; http://ir.uitm.edu.my/id/eprint/44889/

Mangosteen fruit was known and widely used as medical purpose such as medicine to treat abdominal pain, diarrhea and infected wound. This was due to the presences of active compounds such as xanthones which provide remarkable and diverse pharmacological effects such as anticancer, antioxidant, anti-inflammatory and antimicrobial activities. Thus, the fruit hulls of Garcinia mangostana was chosen for further analysis in this project. Specific study on the extraction of ethyl acetate extract from fruit hulls of G. mangostana have successful resulted on the isolation of three phenolic compound, α-mangostin (43), β-mangostin (44) and garcinone D (35) in the column chromatography. The structure of these compounds were identified and elucidated by using spectroscopy methods such as 1H NMR, 13C NMR, infrared (IR) and EIMS