Changes in the Urinary Metabolites in Losartan-Treated Spontaneously Hypertensive Rats / Norasikin Ab Azis ...[et al.]

• Main Authors: Ab Azis, Norasikin, Ahmad Kamal, Mohd Saleh, Radjeni, Zurain, Mediani, Ahmed, Agarwal, Renu
• Format: Article
• Language: English
• Published: Universiti Teknologi MARA Cawangan Selangor 2021
• Subjects: Urinary and reproductive organs; Animal biochemistry; R Medicine (General)
• Online Access: http://ir.uitm.edu.my/id/eprint/44354/1/44354.pdf; http://ir.uitm.edu.my/id/eprint/44354/; https://jchs-medicine.uitm.edu.my/index.php

Introduction: This study examined the association of losartan induced changes in urinary metabolomic profile with the changes in blood pressure (BP) and renin-angiotensin- aldosterone system (RAAS) in spontaneously hypertensive rats (SHR). Methods: Male SHR were administered with either 0.5 mL of di...