A Rare Presentation of Cutaneous Metastases in Advanced Lung Adenocarcinoma / Liyana Dhamirah Aminuddin ... [et al.]

• Main Authors: Aminuddin, Liyana Dhamirah, Ab Wahab, Sabrina, Shariffudin, Suhaili, Taib, Tarita
• Format: Article
• Language: English
• Published: Universiti Teknologi MARA Cawangan Selangor 2020
• Subjects: Neoplasms. Tumors. Oncology; Cancer; Diseases of the lungs
• Online Access: http://ir.uitm.edu.my/id/eprint/44199/1/44199.pdf; http://ir.uitm.edu.my/id/eprint/44199/; https://jchs-medicine.uitm.edu.my/index.php

Patients with lung cancer may present with respiratory and systemic symptoms. However, cutaneous metastases from primary lung cancer is a rare phenomenon, especially in women, that signifies a poor prognosis. This paper reported a case regarding a 71-year-old woman who was first presented with a cutaneous nodule over the year. Her condition was further progressed to multiple lesions on the back and abdomen, dyspnoea, haemoptysis and weight loss. The results of the skin lesion biopsy exhibited metastatic lung adenocarcinoma with positive immunohistochemistry for thyroid transcription factor 1 (TTF1) and cytokeratin 7 (CK- 7). Computed tomography (CT) scan was conducted, and it revealed a left upper lobe lung mass. The patient was subsequently scheduled for additional management, but she had succumbed to complications of pulmonary embolism before the necessary interventions could be provided. In this particular case presentation, the biopsy of cutaneous lesions obtained had revealed an undiagnosed primary malignancy.