Synthesis of anthraquinone analogues and their antiplasmodial activity / Nor Hadiani Ismail, Rohaya Ahmad and Che Puteh Osman

• Main Authors: Ismail, Nor Hadiani, Ahmad, Rohaya, Osman, Che Puteh
• Format: Research Reports
• Language: English
• Published: Research Management Institute (RMI) 2011
• Subjects: Aromatic compounds
• Online Access: https://ir.uitm.edu.my/id/eprint/26361/1/LP_NOR%20HADIANI%20ISMAIL%20RMI%2011_5.pdf; https://ir.uitm.edu.my/id/eprint/26361/

Several anthraquinones such as 2-formyl-3-hydroxyanthraquinone, damncanthal and emodin were known antiplasmodial agents. Anthraquinones like other aromatic substances may undergo bioreduction and produce oxygen radicals thereby rendering the malarial parasite more susceptible to oxidative stress lea...