Preliminary study on antifungal properties of hibiscus rosa­-sinensis leave extract via in vitro approach / Amira Abdul Rahim

• Main Author: Abdul Rahim, Amira
• Format: Thesis
• Language: English
• Published: 2013
• Subjects: Pharmacognosy. Pharmaceutical substances (Plant, animal, and inorganic)
• Online Access: https://ir.uitm.edu.my/id/eprint/109620/1/109620.PDF; https://ir.uitm.edu.my/id/eprint/109620/

Skin disorder can cause a significant discomfort which can affect ones confidence level and maintenance costs. Study on natural resources has become popular recently as the available treatments are unable to prevent the reoccurrence of these skin disorders and have certain limitations. Hibiscus rosa-sinensis is a genus of flowering plant in the mallow family known as Malvaceae. Various parts of Hibiscus rosa- sinensis posses' significant medicinal effects based on research done all over the world. The aim of this study was to evaluate the antifungal properties of Hibiscus rosa-sinensis aqueous and ethanolic leave extract against Malassezia furfur and Malassezia pachydermatis via in vitro approach. The agar-well diffusion method was used to assess the antifungal activity of the extracts. Ketoconazole 16µg/µl was used as standard references. The results demonstrated that both aqueous and ethanolic leave extract of Hibiscus rosa-sinensis with concentration of 0.1g/ml, 1g/ml, 5g/ml, and 10g/ml did not possesses inhibitory activity against Mfurfur and M.pachydermatis as compared to standard reference. The reported observation suggests that aqueous and ethanolic leave extract of Hibiscus rosa-sinensis does not exert antifungal properties against Mfurfur and M.pachydermatis.