Cover Image

Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah

Hyperhomocysteinemia (HHcy) has been linked to an increased risk of cardiovascular diseases. High levels of homocysteine (Hcy) cause damage to endothelial cells by promoting endoplasmic reticulum (ER) stress that increases reactive oxygen species (ROS), and cause endothelial nitric oxide synthase (e...

Full description

Saved in:
Bibliographic Details
Main Author: M. Sofiullah, Siti Sarah
Format: Thesis
Language:English
Published: 2024
Subjects:
Diseases of the circulatory (Cardiovascular) system
Online Access:https://ir.uitm.edu.my/id/eprint/107225/1/107225.pdf
https://ir.uitm.edu.my/id/eprint/107225/
Tags: Add Tag
No Tags, Be the first to tag this record!
id my.uitm.ir.107225
record_format eprints
spelling my.uitm.ir.1072252024-12-04T08:27:17Z https://ir.uitm.edu.my/id/eprint/107225/ Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah M. Sofiullah, Siti Sarah Diseases of the circulatory (Cardiovascular) system Hyperhomocysteinemia (HHcy) has been linked to an increased risk of cardiovascular diseases. High levels of homocysteine (Hcy) cause damage to endothelial cells by promoting endoplasmic reticulum (ER) stress that increases reactive oxygen species (ROS), and cause endothelial nitric oxide synthase (eNOS) uncoupling, leading to endothelial dysfunction. Thymoquinone (TQ) is the major active ingredient in Nigella sativa seeds volatile oil and is shown to have a cardioprotective effect. 2024 Thesis NonPeerReviewed text en https://ir.uitm.edu.my/id/eprint/107225/1/107225.pdf Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah. (2024) Masters thesis, thesis, Universiti Teknologi MARA (UiTM). <http://terminalib.uitm.edu.my/107225.pdf>
institution Universiti Teknologi Mara
building Tun Abdul Razak Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Mara
content_source UiTM Institutional Repository
url_provider http://ir.uitm.edu.my/
language English
topic Diseases of the circulatory (Cardiovascular) system
spellingShingle Diseases of the circulatory (Cardiovascular) system
M. Sofiullah, Siti Sarah
Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah
description Hyperhomocysteinemia (HHcy) has been linked to an increased risk of cardiovascular diseases. High levels of homocysteine (Hcy) cause damage to endothelial cells by promoting endoplasmic reticulum (ER) stress that increases reactive oxygen species (ROS), and cause endothelial nitric oxide synthase (eNOS) uncoupling, leading to endothelial dysfunction. Thymoquinone (TQ) is the major active ingredient in Nigella sativa seeds volatile oil and is shown to have a cardioprotective effect.
format Thesis
author M. Sofiullah, Siti Sarah
author_facet M. Sofiullah, Siti Sarah
author_sort M. Sofiullah, Siti Sarah
title Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah
title_short Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah
title_full Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah
title_fullStr Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah
title_full_unstemmed Elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / Siti Sarah M. Sofiullah
title_sort elucidating vascular protective effect and molecular mechanisms of thymoquinone in homocysteine-induced endothelial dysfunction: ex vivo and in vitro model / siti sarah m. sofiullah
publishDate 2024
url https://ir.uitm.edu.my/id/eprint/107225/1/107225.pdf
https://ir.uitm.edu.my/id/eprint/107225/
_version_ 1817847398065504256
score 13.222552

Similar Items