Antibacterial activity of terrestrial snail mucus (Achatina fulica) mediated green synthesis of silver nanoparticles / Fatin Nur Fateha S Abdul Jalil

• Main Author: S Abdul Jalil, Fatin Nur Fateha
• Format: Student Project
• Language: English
• Published: 2022
• Subjects: Immunology
• Online Access: https://ir.uitm.edu.my/id/eprint/102399/1/102399.pdf; https://ir.uitm.edu.my/id/eprint/102399/

The growth and bacterial resistance necessitate the development of new anti-infective agents, with silver nanoparticles (AgNPs) exhibiting particularly intriguing features. AgNPs exert antibacterial activity via a variety of molecular pathways. This study carried out antibacterial activity of a recently described type of AgNPs using A. fulica snail mucus (SM) where their protein determined. Characterization of AgNPs-SM was done by UV-Visible spectrophotometer (UV-Vis), Fourier-Transform Infrared spectroscopy (FTIR) analysis and Scanning Electron Microscopy (SEM). Their visible colour changes determined along with UV-Vis absorption spectrum plasmon peak at 404.9 nm showed the formation of AgNPs. The FTIR spectra was observed the variation of functional groups existing and the SEM confirmed the AgNPs physical shape in nanoscale size. Antibacterial activities mediated AgNPs was conducted by disc diffusion method with different concentrations. The outcome from the study showed that AgNPs-SM had significant antibacterial activity against Bacillus licheniformis (Gram-positive bacteria) and Escherichia coli (Gram-negative bacteria).