Synthesis, characterization and antimicrobial studies of hydroxamic acid complexes / Syazana Zawani Aziz Jaafar

• Main Author: Aziz Jaafar, Syazana Zawani
• Format: Thesis
• Language: English
• Published: 2008
• Online Access: https://ir.uitm.edu.my/id/eprint/100937/1/100937.pdf; https://ir.uitm.edu.my/id/eprint/100937/

Zinc and Copper(III) hydroxamato complexes are synthesized and characterized by elemental analysis, Fourier-transform infrared spectroscopy, conductivity and magnetic susceptibility measurements. The molecular compositions of the synthesized complexes are found to be ZnL3 and CuL2, respectively. The antimicrobial activity of these complexes is determined by disc diffusion method against the target microorganisms - Staphylococcus aureus, Methicillin Resistant Staphylococcus aureus, Escherichia coli and Aspergillus niger. The antimicrobial activities of benzohydroxamic acid and its complexes were compared. It is observed that the ligand did not show any antibacterial activity. However, the inhibitive property against Methicillin Resistant Staphylococcus aureus is slightly seen upon complexation of benzohydroxamic acid with copper.