Development of nanoparticle-assisted PCR assay in the rapid detection of brain-eating amoebae

• Main Authors: Gabriel, Shobana *, Rasheed, A. K. *, Siddiqui, Ruqaiyyah Bano *, Appaturi, Jimmy Nelson, Leo, Bey Fen
• Format: Article
• Published: Springer Verlag 2018
• Subjects: QH301 Biology
• Online Access: http://eprints.sunway.edu.my/981/; https://link.springer.com/article/10.1007%2Fs00436-018-5864-0

Brain-eating amoebae (Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri) have gained increasing attention owing to their capacity to produce severe human and animal infections involving the brain. Early detection is a pre-requisite in successful prognosis. Here, we developed a nanoPCR as...