Characterization of significant molecular determinants of virulence of Enterovirus 71 sub-genotype B4 in Rhabdomyosarcoma cells

• Main Authors: Yee, Isabel Pin Tsin *, Reham Ahmed Hashim Mohamed, *, Ong, Seng Kai *, Tan, Kuan Onn *, Poh, Chit Laa *
• Format: Article
• Language: English
• Published: Elsevier 2017
• Subjects: QH301 Biology
• Online Access: http://eprints.sunway.edu.my/503/1/Isabelle%20Yee.pdf; http://eprints.sunway.edu.my/503/; https://doi.org/10.1016/j.virusres.2017.07.010

One of the leading causes of the hand, foot and mouth disease (HFMD) is Enterovirus 71(EV-A71), displaying symptoms such as fever and ulcers in children but some strains can produce cardiopulmonary oedema which leads to death. There is no FDA-approved vaccine for prevention of severe HFMD. The molec...