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Targeting brain-eating amoebae infections

Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite...

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Main Authors: Khan, Naveed Ahmed *, Ong, Timothy Yu Yee *, Siddiqui, Ruqaiyyah Bano *
Format: Article
Language:English
Published: American Chemical Society 2017
Subjects:
Q Science (General)
QR355 Virology
Online Access:http://eprints.sunway.edu.my/485/1/Targeting%20brain%20eating%20amoebae%20infections.pdf
http://eprints.sunway.edu.my/485/
http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.7b00049
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spelling my.sunway.eprints.4852020-01-23T03:28:08Z http://eprints.sunway.edu.my/485/ Targeting brain-eating amoebae infections Khan, Naveed Ahmed * Ong, Timothy Yu Yee * Siddiqui, Ruqaiyyah Bano * Q Science (General) QR355 Virology Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite viability without affecting the host cells, with an eye to improve formulation of drugs and/or administration of drugs against brain-eating amoebae. American Chemical Society 2017-02-22 Article PeerReviewed text en http://eprints.sunway.edu.my/485/1/Targeting%20brain%20eating%20amoebae%20infections.pdf Khan, Naveed Ahmed * and Ong, Timothy Yu Yee * and Siddiqui, Ruqaiyyah Bano * (2017) Targeting brain-eating amoebae infections. ACS Chemical Neuroscience, 8 (4). pp. 687-688. ISSN 1948-7193 http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.7b00049 DOI: 10.1021/acschemneuro.7b00049
institution Sunway University
building Sunway Campus Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Sunway University
content_source Sunway Institutional Repository
url_provider http://eprints.sunway.edu.my/
language English
topic Q Science (General)
QR355 Virology
spellingShingle Q Science (General)
QR355 Virology
Khan, Naveed Ahmed *
Ong, Timothy Yu Yee *
Siddiqui, Ruqaiyyah Bano *
Targeting brain-eating amoebae infections
description Brain infections due to Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri often lead to death. Despite differences in the preferential sites of infection in the brain, the mode of delivery of drugs is often intravenous. Here, we discuss targeted therapeutic approach to affect parasite viability without affecting the host cells, with an eye to improve formulation of drugs and/or administration of drugs against brain-eating amoebae.
format Article
author Khan, Naveed Ahmed *
Ong, Timothy Yu Yee *
Siddiqui, Ruqaiyyah Bano *
author_facet Khan, Naveed Ahmed *
Ong, Timothy Yu Yee *
Siddiqui, Ruqaiyyah Bano *
author_sort Khan, Naveed Ahmed *
title Targeting brain-eating amoebae infections
title_short Targeting brain-eating amoebae infections
title_full Targeting brain-eating amoebae infections
title_fullStr Targeting brain-eating amoebae infections
title_full_unstemmed Targeting brain-eating amoebae infections
title_sort targeting brain-eating amoebae infections
publisher American Chemical Society
publishDate 2017
url http://eprints.sunway.edu.my/485/1/Targeting%20brain%20eating%20amoebae%20infections.pdf
http://eprints.sunway.edu.my/485/
http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.7b00049
_version_ 1657490650973601792
score 13.211869

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