Histone Deacetylase Inhibitors Restore Cancer Cell Sensitivity towards T Lymphocytes Mediated Cytotoxicity in Pancreatic Cancer

• Main Authors: Looi, Chin King, Gan, Li Lian, Sim, Wynne, Hii, Ling Wei, Chung, Felicia Fei Lei *, Leong, Chee Onn, Lim, Wei Meng, Mai, Chun Wai
• Format: Article
• Language: English
• Published: MDPI 2022
• Subjects: QP Physiology; RC Internal medicine
• Online Access: http://eprints.sunway.edu.my/3107/1/Felicia%20Chung_Histone%20deacetylase%20inhibitors%20restore%20cancer%20cell%20sensitivity%20towards%20T%20lymphhocytes.pdf; http://eprints.sunway.edu.my/3107/; https://doi.org/10.3390/cancers14153709

Despite medical advancements, the prognosis of pancreatic ductal adenocarcinoma (PDAC) has not improved significantly over the past 50 years. By utilising the large-scale genomic datasets available from the Australia Pancreatic Cancer Project (PACA-AU) and The Cancer Genomic Atlas Project (TCGA-PAAD...