Prediction of Low-Dose Aspirin-Induced Gastric Toxicity Using Nuclear Magnetic Resonance Spectroscopy-Based Pharmacometabolomics in Rats
Background: Low-dose aspirin (LDA) is the backbone for secondary prevention of coronary artery disease, although limited by gastric toxicity. This study aimed to identify novel metabolites that could predict LDA-induced gastric toxicity using pharmacometabolomics. Methods: Pre-dosed urine samples...
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Main Authors: | Abubakar, Sha'aban, Hadzliana, Zainal, Nor Azlina, Khalil, Fatimatuzzahra', Abd Aziz, Ch'ng, Ewe Seng *, Teh, Chin Hoe, Mustapha, Mohammed, Baharudin, Ibrahim |
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Format: | Article |
Published: |
MDPI
2022
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Online Access: | http://eprints.sunway.edu.my/3040/ https://doi.org/10.3390/molecules27072126 |
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