Phytochemical screening and Antioxidant activity of Cananga odorata extract
Plants are the natural source for the antioxidants from plants source is boon for the investigators. Present study was aimed to study the antioxidant activity and phytochemical screening of Cananga odorata (Lam.) Hook. f. & Thomson extract. Study involved preparation hydroalcoholic extract of Ca...
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Research Journal of Pharmacy and Technology
2022
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my.sunway.eprints.30332024-08-08T03:09:25Z http://eprints.sunway.edu.my/3033/ Phytochemical screening and Antioxidant activity of Cananga odorata extract Chew, Khe Jiea Fuloria, Shivkanya Vetriselvan, Subramaniyan Mahendran, Sekar Kathiresan, V Sathasivam Saminathan, Kayarohanam Wu, Yuan Seng * Venkata Sathya, Saiappala Raju Velaga Ashok Kumar, Janakiraman Mohammad Nazmul, Hasan Mazia Fuloria, Neeraj Kumar QD Chemistry QK Botany QP Physiology Plants are the natural source for the antioxidants from plants source is boon for the investigators. Present study was aimed to study the antioxidant activity and phytochemical screening of Cananga odorata (Lam.) Hook. f. & Thomson extract. Study involved preparation hydroalcoholic extract of Cananga odorata leaves (HECOL) using maceration method, followed by its phytochemical screening and antioxidant activity. The HECOL was subjected to determination of total phenolic content (TPC) and total flavonoid content (TFC), and DPPH (1,1-Diphenyl-2-picryl hydrazyl) radical scavenging assay for determination of antioxidant activity. Maceration of C. odorata using hydroalcoholic solvent offered dark brown colored HECOL. Phytochemical screening of HECOL exhibited presence of carbohydrates, mucilage, fats and oils, volatile oils, anthraquinone glycosides, flavonoids, alkaloids, tannins and phenolic compounds. For TPC the gallic acid equivalent of HECOL was found to be 0.507 mg GAE/g. Whereas for TFC, the rutin equivalent of HECOL was found to be 0.2224mg RE/g. The antioxidant activity of HECOL was estimated to be 120.44μg/ml (IC50). Based on the experimental results, present study concludes that HECOL possess the significant antioxidant potential. This study also recommends that antioxidant activity potential of C. odorata leaves should be further explored using different solvent extracts. Research Journal of Pharmacy and Technology 2022 Article PeerReviewed Chew, Khe Jiea and Fuloria, Shivkanya and Vetriselvan, Subramaniyan and Mahendran, Sekar and Kathiresan, V Sathasivam and Saminathan, Kayarohanam and Wu, Yuan Seng * and Venkata Sathya, Saiappala Raju Velaga and Ashok Kumar, Janakiraman and Mohammad Nazmul, Hasan Mazia and Fuloria, Neeraj Kumar (2022) Phytochemical screening and Antioxidant activity of Cananga odorata extract. Research Journal of Pharmacy and Technology, 15 (3). pp. 1230-1234. ISSN 0974-360X https://rjptonline.org/AbstractView.aspx?PID=2022-15-3-48 10.52711/0974-360X.2022.00205 |
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QD Chemistry QK Botany QP Physiology Chew, Khe Jiea Fuloria, Shivkanya Vetriselvan, Subramaniyan Mahendran, Sekar Kathiresan, V Sathasivam Saminathan, Kayarohanam Wu, Yuan Seng * Venkata Sathya, Saiappala Raju Velaga Ashok Kumar, Janakiraman Mohammad Nazmul, Hasan Mazia Fuloria, Neeraj Kumar Phytochemical screening and Antioxidant activity of Cananga odorata extract |
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Plants are the natural source for the antioxidants from plants source is boon for the investigators. Present study was aimed to study the antioxidant activity and phytochemical screening of Cananga odorata (Lam.) Hook. f. & Thomson extract. Study involved preparation hydroalcoholic extract of Cananga odorata leaves (HECOL) using maceration method, followed by its phytochemical screening and antioxidant activity. The HECOL was subjected to determination of total phenolic content (TPC) and total flavonoid content (TFC), and DPPH (1,1-Diphenyl-2-picryl hydrazyl) radical scavenging assay for determination of antioxidant activity. Maceration of C. odorata using hydroalcoholic solvent offered dark brown colored HECOL. Phytochemical screening of HECOL exhibited presence of carbohydrates, mucilage, fats and oils, volatile oils, anthraquinone glycosides, flavonoids, alkaloids, tannins and phenolic compounds. For TPC the gallic acid equivalent of HECOL was found to be 0.507 mg GAE/g. Whereas for TFC, the rutin equivalent of HECOL was found to be 0.2224mg RE/g. The antioxidant activity of HECOL was estimated to be 120.44μg/ml (IC50). Based on the experimental results, present study concludes that HECOL possess the significant antioxidant potential. This study also recommends that antioxidant activity potential of C. odorata leaves should be further explored using different solvent extracts. |
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Chew, Khe Jiea Fuloria, Shivkanya Vetriselvan, Subramaniyan Mahendran, Sekar Kathiresan, V Sathasivam Saminathan, Kayarohanam Wu, Yuan Seng * Venkata Sathya, Saiappala Raju Velaga Ashok Kumar, Janakiraman Mohammad Nazmul, Hasan Mazia Fuloria, Neeraj Kumar |
author_facet |
Chew, Khe Jiea Fuloria, Shivkanya Vetriselvan, Subramaniyan Mahendran, Sekar Kathiresan, V Sathasivam Saminathan, Kayarohanam Wu, Yuan Seng * Venkata Sathya, Saiappala Raju Velaga Ashok Kumar, Janakiraman Mohammad Nazmul, Hasan Mazia Fuloria, Neeraj Kumar |
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Chew, Khe Jiea |
title |
Phytochemical screening and Antioxidant activity of Cananga odorata extract |
title_short |
Phytochemical screening and Antioxidant activity of Cananga odorata extract |
title_full |
Phytochemical screening and Antioxidant activity of Cananga odorata extract |
title_fullStr |
Phytochemical screening and Antioxidant activity of Cananga odorata extract |
title_full_unstemmed |
Phytochemical screening and Antioxidant activity of Cananga odorata extract |
title_sort |
phytochemical screening and antioxidant activity of cananga odorata extract |
publisher |
Research Journal of Pharmacy and Technology |
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2022 |
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http://eprints.sunway.edu.my/3033/ https://rjptonline.org/AbstractView.aspx?PID=2022-15-3-48 |
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