Fabrication of cellulose nanocrystals as potential anticancer drug delivery systems for colorectal cancer treatment

• Main Authors: Mostafa, Yusefi, Soon, Michiele Lee Kiun *, Teow, Sin Yeang *, Monchouguy, Elaine Irene, Bibi Morheen, Haleema Mooneerah Neerooa, Zahra, Izadiyan, Jahangirian, Hossein, Rafiee-Moghaddam, Roshanak, Webster, Thomas J., Kamyar, Shameli
• Format: Article
• Published: Elsevier 2022
• Subjects: RC Internal medicine; RS Pharmacy and materia medica
• Online Access: http://eprints.sunway.edu.my/3023/; https://doi.org/10.1016/j.ijbiomac.2021.12.189

Polysaccharide nanocrystals have great potential to be used as improved drug carriers due to their low cost, high biodegradability, and biocompatibility. This study reports the synthesis of cellulose nanocrystals (CNC) loaded with 5-fluorouracil (CNC/5FU) to evaluate their anticancer activity agains...