Alpha-Mangostin Activates MOAP-1 Tumor Suppressor and Mitochondrial Signaling in MCF-7 Human Breast Cancer Cells

• Main Authors: Simon, Samson Eugin, Lim, Hui Sin *, Fairen, Angelin Jayakumar *, Tan, Ee Wern *, Tan, Kuan Onn *
• Format: Article
• Language: English
• Published: Wiley Open Access 2022
• Subjects: QK Botany; RC Internal medicine; RM Therapeutics. Pharmacology
• Online Access: http://eprints.sunway.edu.my/2982/1/Tan%20Ee%20Wern_Alpha-mangostin%20activates%20MOAP-1%20tumor%20suppressor.pdf; http://eprints.sunway.edu.my/2982/; https://doi.org/10.1155/2022/7548191

α-Mangostin, one of the major constituents of Garcinia mangostana, has been reported to possess several biological activities, including antioxidant, anti-inflammatory, antibacterial, and cytotoxic activities associated with the inhibition of cell proliferation and activation of apoptosis. However,...