Aggregatibacter actinomycetemcomitans as the Aetiological Cause of Rheumatoid Arthritis: What Are the Unsolved Puzzles?
Leukotoxin A (LtxA) is the major virulence factor of an oral bacterium known as Aggregatibacter actinomycetemcomitans (Aa). LtxA is associated with elevated levels of anti-citrullinated protein antibodies (ACPA) in rheumatoid arthritis (RA) patients. LtxA targets leukocytes and triggers an influx of...
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Main Authors: | Looh, Sung Cheng, Soo, Zoey May Pheng, Wong, Jia Jia, Yam, Hok Chai, Chow, Sook Khuan, Hwang, Jung Shan * |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022
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Subjects: | |
Online Access: | http://eprints.sunway.edu.my/2981/1/Hwang%20Jun%20Shan_Aggregatibacter%20actinomycetemcomitans%20as%20the%20aetiological%20cause%20of%20rheumatoid%20arthritis.pdf http://eprints.sunway.edu.my/2981/ https://doi.org/10.3390/toxins14010050 |
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