Evaluation of S-substituted-2-mercaptobenzimidazole analogs for urease inhibitory and DPPH radical scavenging potential: synthesis, bioactivity, and molecular docking study

• Main Authors: Ata, Amber, Khan, Khalid Mohammed, Lateef, Mehreen, Salar, Uzma, Ayaz, Anwar *, Wadood, Abdul, Rehman, Ashfaq Ur, Hameed, Shehryar, Zafar, Fatima, Taha, Muhammad, Perveen, Shahnaz
• Format: Article
• Published: Springer 2023
• Subjects: QD Chemistry; RC Internal medicine
• Online Access: http://eprints.sunway.edu.my/2914/; https://link.springer.com/article/10.1007/s13738-022-02653-1

Several S-substituted-2-mercaptobenzimidazole derivatives 1–34 were synthesized by reacting 2-mercaptobenzimidazole with a variety of substituted benzyl bromide and characterized with the help of various spectroscopic techniques. All synthetic compounds were evaluated for urease inhibitory and DPPH...