Malabaricones from the fruit of Myristica cinnamomea King as potential agents against Acanthamoeba castellanii

• Main Authors: Usman, Ahmed *, Sivasothy, Yasodha, Khan, Khalid Mohammed, Khan, Naveed Ahmed *, Siti Mariam, Abdul Wahab, Khalijah, Awang, Muhamad, Aqmal Othman, Ayaz, Anwar *
• Format: Article
• Published: Elsevier 2023
• Subjects: QD Chemistry; QL Zoology; RS Pharmacy and materia medica
• Online Access: http://eprints.sunway.edu.my/2681/; https://doi.org/10.1016/j.actatropica.2023.107033

Acanthamoeba castellanii is an opportunistic free-living amoeba (FLA) pathogen which can cause fatal central nervous system (CNS) infection, granulomatous amoebic encephalitis (GAE) and potentially blinding ocular infection, Acanthamoeba keratitis (AK). Acanthamoeba species remain a challenging prot...