Evaluation of human embryonic stem cells and their differentiatedfibroblastic progenies as cellular models for in vitro genotoxicity screening
This study evaluated human embryonic stem cells (hESC) and their differentiated fibroblastic progeniesas cellular models for genotoxicity screening. The DNA damage response of hESCs and their differentiated fibroblastic progenies were compared to a fibroblastic cell line (HEPM, CRL1486) and primary...
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Main Authors: | Vinoth, Kumar Jayaseelan, Manikandan, Jayapal, Sethu, Swaminathan, Balakrishan, Lakshmidevi, Heng, Alexis Boon Chin *, Lu, Kai, Hande, Manoor Prakash, Cao, Tong |
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Format: | Article |
Published: |
Elsevier
2014
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Subjects: | |
Online Access: | http://eprints.sunway.edu.my/265/ http://www.sciencedirect.com/science/article/pii/S0168165614002405 http://dx.doi.org/10.1016/j.jbiotec.2014.05.009 |
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