Development of a novel direct compressible co-processed excipient and its application for formulation of Mirtazapine orally disintegrating tablets

• Main Authors: Loke, Ying Hui, Chew, Yik-Ling, Ashok Kumar, Janakiraman, Lee, Siew-Keah, A.B.M. Helal, Uddin, Goh, Fu Choon, Kee, Phei Er, Ng, Hui Suan, Long, Chiau Ming *, Liew, Kai Bin
• Format: Article
• Published: Taylor and Francis Group 2024
• Subjects: QD Chemistry; RS Pharmacy and materia medica
• Online Access: http://eprints.sunway.edu.my/2605/; https://doi.org/10.1080/03639045.2023.2294095

Introduction Orally disintegrating tablets (ODTs) are designed to dissolve in the oral cavity within 3 min, providing a convenient option for patients as they can be taken without water. Direct compression is the most common method used for ODTs formulations. However, the availability of single com...