Unveiling the antinociceptive mechanisms of Methyl-2-(4-chloro-phenyl)-5-benzoxazoleacetate: insights from nociceptive assays in mice

• Main Authors: Jarrar, Q, Ayoub, R, Jarrar, Y, Jaffal, H, Goh, K W, Long, Chiau Ming *, Moshawih, S, Sirhan, A
• Format: Article
• Published: European Review for Medical and Pharmacological Sciences 2024
• Subjects: QP Physiology; RA Public aspects of medicine; RM Therapeutics. Pharmacology
• Online Access: http://eprints.sunway.edu.my/2583/

Objective: Methyl-2-(4-chloro- phenyl)-5-benzoxazoleacetate (MCBA), a synthetic benzoxazole derivative with established antipsoriatic efficacy, was investigated for potential antinociceptive effects. This study employs various nociceptive assays in mice to elucidate MCBA's antinociceptive mecha...