Two conformational polymorphs of a bioactive pyrazolo[3,4-d]pyrimidine

• Main Authors: Tan, Sang Loon *, Tan, Yee Seng *, Ng, Jia Hui, Dolzhenko, Anton V, Tiekink, Edward R. T. *
• Format: Article
• Language: English
• Published: MDPI 2023
• Subjects: QD Chemistry
• Online Access: http://eprints.sunway.edu.my/2289/1/crystals%202023%2013%20974.pdf; http://eprints.sunway.edu.my/2289/; https://www.mdpi.com/2073-4352/13/6/974

Two monoclinic (P21/c; Z′ = 1) polymorphs, α (from methanol) and β (from ethanol, n-propanol and iso-propanol), of a bioactive pyrazolo[3,4-d]pyrimidine derivative have been isolated and characterised by X-ray crystallography as well as by a range of computational chemistry techniques. The different...