Association between autophagy and KRAS mutation with clinicopathological variables in colorectal cancer patients

• Main Authors: Awi, Noel Jacques, Yap, Hooi Yeen, Subasri, A., Low, John Seng-Hooi, Peh, Kaik-Boo, Peh, Suat Cheng *, Lee, C. S., Teow, Sin Yeang *
• Format: Article
• Language: English
• Published: College of Pathologists, Academy of Medicine Malaysia 2021
• Subjects: RC0254 Neoplasms. Tumors. Oncology (including Cancer)
• Online Access: http://eprints.sunway.edu.my/1845/1/Teow%20Sin%20Yeang%20Association%20between%20autophagy%20and%20kras%20mutation%20with%20clinicopathological%20variables%20in%20colorectal%20cancer%20patients.pdf; http://eprints.sunway.edu.my/1845/; http://www.mjpath.org.my/index.php

Autophagy is a host defensive mechanism responsible for eliminating harmful cellular components through lysosomal degradation. Autophagy has been known to either promote or suppress various cancers including colorectal cancer (CRC). KRAS mutation serves as an important predictive marker for epiderm...