Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography
Highly crystalline titanium dioxide nanoparticles (TiO2 -NPs) are synthesized via a simple hydrothermal technique. After structural and compositional analysis, the as-synthesized unmodified TiO2 -NPs are tested for improvement in two modes of kilovoltage radiation therapy and singlephoton emission...
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my.sunway.eprints.16682021-04-19T03:59:38Z http://eprints.sunway.edu.my/1668/ Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography Khalid, A. Ahmad, P. Alharthi, A. I. Muhammad, S. Khandaker, Mayeen Uddin * Faruque, M. R. I. Din, I. U. Alotaibi, M. A. R895-920 Medical Physics/Medical Radiology Highly crystalline titanium dioxide nanoparticles (TiO2 -NPs) are synthesized via a simple hydrothermal technique. After structural and compositional analysis, the as-synthesized unmodified TiO2 -NPs are tested for improvement in two modes of kilovoltage radiation therapy and singlephoton emission computed tomography (SPECT)/computed tomography (CT). Our results show that the unmodified TiO2 -NPs provide an observable enhancement in CT scan image contrast ranging from 0 ± 3 HU (without NPs) to 283.7 ± 3 HU (0.23 g/mL). TiO2 -NPs has excellent biocompatibility, selective uptake at target sites, and reduced toxicity. The unmodified TiO2 -NPs as a contrast agent can significantly improve the existing methods of diagnosing and treating cancer. MDPI 2021 Article PeerReviewed text en cc_by_nc_4 http://eprints.sunway.edu.my/1668/1/Mayeen%20Unmodified%20Titanium.pdf Khalid, A. and Ahmad, P. and Alharthi, A. I. and Muhammad, S. and Khandaker, Mayeen Uddin * and Faruque, M. R. I. and Din, I. U. and Alotaibi, M. A. (2021) Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography. Crystals, 11 (2). p. 171. ISSN 2073-4352 http://doi.org/10.3390/cryst11020171 doi:10.3390/cryst11020171 |
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R895-920 Medical Physics/Medical Radiology Khalid, A. Ahmad, P. Alharthi, A. I. Muhammad, S. Khandaker, Mayeen Uddin * Faruque, M. R. I. Din, I. U. Alotaibi, M. A. Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
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Highly crystalline titanium dioxide nanoparticles (TiO2
-NPs) are synthesized via a simple hydrothermal technique. After structural and compositional analysis, the as-synthesized unmodified TiO2 -NPs are tested for improvement in two modes of kilovoltage radiation therapy and singlephoton emission computed tomography (SPECT)/computed tomography (CT). Our results show that the unmodified TiO2
-NPs provide an observable enhancement in CT scan image contrast ranging from 0 ± 3 HU (without NPs) to 283.7 ± 3 HU (0.23 g/mL). TiO2 -NPs has excellent biocompatibility,
selective uptake at target sites, and reduced toxicity. The unmodified TiO2 -NPs as a contrast agent can significantly improve the existing methods of diagnosing and treating cancer. |
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Article |
author |
Khalid, A. Ahmad, P. Alharthi, A. I. Muhammad, S. Khandaker, Mayeen Uddin * Faruque, M. R. I. Din, I. U. Alotaibi, M. A. |
author_facet |
Khalid, A. Ahmad, P. Alharthi, A. I. Muhammad, S. Khandaker, Mayeen Uddin * Faruque, M. R. I. Din, I. U. Alotaibi, M. A. |
author_sort |
Khalid, A. |
title |
Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
title_short |
Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
title_full |
Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
title_fullStr |
Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
title_full_unstemmed |
Unmodified Titanium Dioxide Nanoparticles as a potential contrast agent in photon emission computed tomography |
title_sort |
unmodified titanium dioxide nanoparticles as a potential contrast agent in photon emission computed tomography |
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MDPI |
publishDate |
2021 |
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http://eprints.sunway.edu.my/1668/1/Mayeen%20Unmodified%20Titanium.pdf http://eprints.sunway.edu.my/1668/ http://doi.org/10.3390/cryst11020171 |
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1698699938889728000 |
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13.18916 |