Role of microRNAs in antiviral responses to dengue infection

• Main Authors: Wong, Rui Rui, Noraini Abd Aziz, *, Sarah Affendi,, Poh, Chit Laa *
• Format: Article
• Language: English
• Published: BMC 2020
• Subjects: QR355 Virology
• Online Access: http://eprints.sunway.edu.my/1202/1/Noraini%20Abd%20Aziz%20Role%20of%20microRNAs.pdf; http://eprints.sunway.edu.my/1202/; http://doi.org/10.1186/s12929-019-0614-x

Dengue virus (DENV) is the etiological agent of dengue fever. Severe dengue could be fatal and there is currently no effective antiviral agent or vaccine. The only licensed vaccine, Dengvaxia, has low efficacy against serotypes 1 and 2. Cellular miRNAs are post-transcriptional regulators that coul...