A decade of sustained selection pressure on two surface sites of the VP1 protein of Enterovirus A71 suggests that immune evasion may be an indirect driver for virulence
Enterovirus A71 (EV-A71) is an emerging pathogen in the Enterovirus A species group. EV-A71 causes hand, foot and mouth disease (HFMD), with virulent variants exhibiting polio-like acute faccid paralysis and other central nervous system manifestations. We analysed all enterovirus A71 complete genome...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Research
2019
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| Subjects: | |
| Online Access: | http://eprints.sunway.edu.my/1098/1/Poh%20CL_A%20decade%20of%20sustained%20selection%20pressure%20on%20two.pdf http://eprints.sunway.edu.my/1098/ http://doi.org/10.1038/s41598-019-41662-8 |
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