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Acetaminophen synthesis and encapsulation using safe mixed-solvents and solution enhanced dispersion by supercritical CO2

Acetaminophen (ACMP) was synthesized in mixed-solvents (H2O-acetone, H2O-dimethyl sulfoxide, H2O-isopropyl alcohol) for purposes of eliminating hazardous dipolar aprotic solvents. The H2O-acetone solvent-pair gave synthesized ACMP yields of 79.2%. Synthesized ACMP samples were encapsulated using s...

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Bibliographic Details
Main Authors: Islam, Tariqul, Sarker, Md. Zaidul Islam Sarker, Helal Uddin, A.B.M., Lee, Richard Smith Jr
Format: Article
Language:English
Published: Elsevier B.V. 2022
Subjects:
QD Chemistry
RM300 Drugs and their action
RS192 Materia Medica-Pharmaceutical Technology
RS403 Materia Medica-Pharmaceutical Chemistry
Online Access:http://irep.iium.edu.my/98711/7/98711_Acetaminophen%20synthesis%20and%20encapsulation%20using%20safe%20mixed-solvents.pdf
http://irep.iium.edu.my/98711/
https://www.elsevier.com/locate/supflu
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http://irep.iium.edu.my/98711/7/98711_Acetaminophen%20synthesis%20and%20encapsulation%20using%20safe%20mixed-solvents.pdf
http://irep.iium.edu.my/98711/
https://www.elsevier.com/locate/supflu

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