Alzheimer’s disease: an update and insights into pathophysiology

• Main Authors: Abubakar, Murtala Bello, Sanusi, Kamaldeen Olalekan, Ugusman, Azizah, Mohamed, Wael Mohamed Yousef, Kamal, Haziq, Ibrahim, Nurul Husna, Ching, Soong Khoo, Kumar, Jaya
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2022
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/97422/7/97422_Alzheimer%E2%80%99s%20disease%20an%20update%20and%20insights%20into%20pathophysiology.pdf; http://irep.iium.edu.my/97422/; https://www.frontiersin.org/articles/10.3389/fnagi.2022.742408/pdf; https://doi.org/10.3389/fnagi.2022.742408

Alzheimer’s disease (AD) is an irreversible brain disorder associated with slow, progressive loss of brain functions mostly in older people. The disease processes start years before the symptoms are manifested at which point most therapies may not be as effective. In the hippocampus, the key protein...