Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants
The differences in pungency of “sirih” imply the probable occurrence of several variants of Piper betle L. in Malaysia. However, the metabolite profiles underlying the pungency of the different variants remain a subject of further research. The differences in metabolite profiles of selected Malaysia...
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my.iium.irep.944032021-12-08T00:31:53Z http://irep.iium.edu.my/94403/ Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants Osman, Muhamad Faris Lee, Soo Yee Sarbini, Shahrul Razid Mohd Faudzi, Siti Munirah Khamis, Shamsul Zainudin, Badrul Hisyam Shaari, Khozirah RS Pharmacy and materia medica RS403 Materia Medica-Pharmaceutical Chemistry The differences in pungency of “sirih” imply the probable occurrence of several variants of Piper betle L. in Malaysia. However, the metabolite profiles underlying the pungency of the different variants remain a subject of further research. The differences in metabolite profiles of selected Malaysian P. betle variants were thus investigated; specifically, the leaf aqueous methanolic extracts and essential oils were analyzed via 1H-NMR and GC-MS metabolomics, respectively. Principal component analysis (PCA) of the 1H-NMR spectral data showed quantitative differences in the metabolite profiles of “sirih melayu” and “sirih india” and revealed an ambiguous group of samples with low acetic acid content, which was identified as Piper rubro-venosum hort. ex Rodigas based on DNA sequences of the internal transcribed spacer 2 (ITS2) region. The finding was supported by PCA of two GC-MS datasets of P. betle samples obtained from several states in Peninsular Malaysia, which displayed clustering of the samples into “sirih melayu” and “sirih india” groups. Higher abundance of chavicol acetate was consistently found to be characteristic of “sirih melayu”. The present research has provided preliminary evidence supporting the notion of occurrence of two P. betle variants in Malaysia based on chemical profiles, which may be related to the different genders of P. betle. MDPI 2021-11-19 Article PeerReviewed application/pdf en http://irep.iium.edu.my/94403/7/94403_Metabolomics-Driven%20discovery%20of%20an%20introduced%20species.pdf application/pdf en http://irep.iium.edu.my/94403/8/94403_Metabolomics-driven%20discovery%20of%20an%20introduced%20species_Scopus.pdf Osman, Muhamad Faris and Lee, Soo Yee and Sarbini, Shahrul Razid and Mohd Faudzi, Siti Munirah and Khamis, Shamsul and Zainudin, Badrul Hisyam and Shaari, Khozirah (2021) Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants. Plants, 10 (11). pp. 1-19. ISSN 2223-7747 https://www.mdpi.com/journal/plants 10.3390/plants10112510 |
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RS Pharmacy and materia medica RS403 Materia Medica-Pharmaceutical Chemistry Osman, Muhamad Faris Lee, Soo Yee Sarbini, Shahrul Razid Mohd Faudzi, Siti Munirah Khamis, Shamsul Zainudin, Badrul Hisyam Shaari, Khozirah Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants |
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The differences in pungency of “sirih” imply the probable occurrence of several variants of Piper betle L. in Malaysia. However, the metabolite profiles underlying the pungency of the different variants remain a subject of further research. The differences in metabolite profiles of selected Malaysian P. betle variants were thus investigated; specifically, the leaf aqueous methanolic extracts and essential oils were analyzed via 1H-NMR and GC-MS metabolomics, respectively. Principal component analysis (PCA) of the 1H-NMR spectral data showed quantitative differences in the metabolite profiles of “sirih melayu” and “sirih india” and revealed an ambiguous group of samples with low acetic acid content, which was identified as Piper rubro-venosum hort. ex Rodigas based on DNA sequences of the internal transcribed spacer 2 (ITS2) region. The finding was supported by PCA of two GC-MS datasets of P. betle samples obtained from several states in Peninsular Malaysia, which displayed clustering of the samples into “sirih melayu” and “sirih india” groups. Higher abundance of chavicol acetate was consistently found to be characteristic of “sirih melayu”. The present research has provided preliminary evidence supporting the notion of occurrence of two P. betle variants in Malaysia based on chemical profiles, which may be related to the different genders of P. betle. |
format |
Article |
author |
Osman, Muhamad Faris Lee, Soo Yee Sarbini, Shahrul Razid Mohd Faudzi, Siti Munirah Khamis, Shamsul Zainudin, Badrul Hisyam Shaari, Khozirah |
author_facet |
Osman, Muhamad Faris Lee, Soo Yee Sarbini, Shahrul Razid Mohd Faudzi, Siti Munirah Khamis, Shamsul Zainudin, Badrul Hisyam Shaari, Khozirah |
author_sort |
Osman, Muhamad Faris |
title |
Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants |
title_short |
Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants |
title_full |
Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants |
title_fullStr |
Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants |
title_full_unstemmed |
Metabolomics-driven discovery of an introduced species and two malaysian piper betle l. Variants |
title_sort |
metabolomics-driven discovery of an introduced species and two malaysian piper betle l. variants |
publisher |
MDPI |
publishDate |
2021 |
url |
http://irep.iium.edu.my/94403/7/94403_Metabolomics-Driven%20discovery%20of%20an%20introduced%20species.pdf http://irep.iium.edu.my/94403/8/94403_Metabolomics-driven%20discovery%20of%20an%20introduced%20species_Scopus.pdf http://irep.iium.edu.my/94403/ https://www.mdpi.com/journal/plants |
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1718925643956092928 |
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13.18916 |