Effect of different carriers on In Vitro and In Vivo drug release behavior of Aceclofenac Proniosomes

• Main Authors: Sammour, Rana M. F., Chatterjee, Bappaditya, Taher, Muhammad, Saleh, Mohammed S.M., Shahiwala, Aliasgar
• Format: Article
• Language: English; English
• Published: NLM (Medline) 2021
• Subjects: RS Pharmacy and materia medica
• Online Access: http://irep.iium.edu.my/92886/1/Current%20Drug%20Delivery%20Bentham.pdf; http://irep.iium.edu.my/92886/7/92886_Effect%20of%20different%20carriers_Scopus.pdf; http://irep.iium.edu.my/92886/

Improved bioavailability of Aceclofenac (ACE) may be achieved through proniosomes, which are considered as one of the most effective drug delivery systems and are expected to represent a valuable approach for the development of better oral dosage form as compared to the existing product. However, the carrier in this system plays a vital role in controlling the drug release and modulating drug dissolution.Accordingly, a comparative study on different carries can give a clear idea about the selection of carries to prepare ACE pronisomes.