The design of paper-based microfluidics channel and sensing area optimization for glucose detection using optical biosensors

• Main Authors: Mohd Salleh, Mohd Hazimin, Azahan, Siti Nurul Fatihah, Mohd Nasir, Mohd Hamzah
• Format: Copyright
• Language: English; English
• Published: 2021
• Subjects: QC Physics; QD Chemistry; QR Microbiology
• Online Access: http://irep.iium.edu.my/90407/1/The%20design%20of%20paper%20based%20microfluidies%20channel%20and%20sensing%20area%20optimization%20for%20glucose%20detection%20using%20optical%20biosensors.pdf; http://irep.iium.edu.my/90407/7/LY2021E02244_THE%20DESIGN%20OF%20PAPER%20BASED%20MICROFLUIDICS%20CHANNEL%20AND%20SENSING%20AREA%20OPTIMIZATION%20FOR%20GLUCOSE%20DETECTION%20USING%20OPTICAL%20BIOSENSORS.pdf; http://irep.iium.edu.my/90407/

This disclosure is mainly focusing on the design of a paper-based microfluidic channel using lateral flow analysis (LFA) for the detection of biomolecules/analytes within the range of 20-50uL.D-glucose standard, glucose oxidase and peroxidase (GOD-POD), buffer solution and various glucose sample concentration were used during the optimization procedure. After calibration and optimization procedure, a specific design was selected and we realized that it has a high potential element for further commercialization due to application in glucose detection that utilizing sweat and saliva sample from human for non-invasive detection methods.