Identification of BRCA1 tumor suppressor gene expression as a DNA repair gene in frozen cleavage embryo cell at IIUM Fertility Centre

• Main Authors: Abdul Razak, Redzuan Nul Hakim, Abdul Wahab, Azantee Yazmie, Ramli, Roszaman, Nik Osman, Nik Mohammed Faez, Nik Hassan, Nik Fakhuruddin, Muhammad, Hussin, Mazlan, Muhammad Alif, Md Isa, Muhammad Lokman
• Format: Article
• Language: English; English
• Published: Malaysian Society for Biochemistry and Molecular Biology 2020
• Subjects: R Medicine (General); RG Gynecology and obstetrics
• Online Access: http://irep.iium.edu.my/90017/7/90017_Identification%20of%20BRCA1%20tumor%20suppressor%20gene%20expression%20as%20a%20DNA%20repair%20gene%20in%20frozen%20cleavage%20embryo%20cell%20at%20IIUM%20Fertility%20Centre_SCOPUS.pdf; http://irep.iium.edu.my/90017/8/90017_Identification%20of%20BRCA1%20tumor%20suppressor%20gene%20expression%20as%20a%20DNA%20repair%20gene%20in%20frozen%20cleavage%20embryo%20cell%20at%20IIUM%20Fertility%20Centre.pdf; http://irep.iium.edu.my/90017/; https://msbmb2010.wixsite.com/mjbmb/general-3

BRCA1 is known as the essential tumor suppressor gene in human that expresses a protein that called breast cancer type 1 susceptibility protein. It has two main functions which are repairing the damaged DNA and also inducing the apoptotic mechanism to eliminate the cell when mutated DNA could not be...