Metformin-induced severe enteropathy: a case report
We highlighted a case of an elderly man with uncontrolled diabetes experienced unbearable chronic diarrhoea for 18 months with the extent of wearing diapers daily. He was having numerous investigation to exclude causes such as malignancy and other red flags chronic diarrhoea causes. His abdominal...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Journal of Critical Reviews
2021
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/89708/7/89708_Metformin-induced%20severe%20enteropathy%20a%20case%20report.pdf http://irep.iium.edu.my/89708/ http://www.jcreview.com/index.php?mno=73237 |
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| Summary: | We highlighted a case of an elderly man with uncontrolled diabetes experienced unbearable chronic diarrhoea for 18
months with the extent of wearing diapers daily. He was having numerous investigation to exclude causes such as
malignancy and other red flags chronic diarrhoea causes. His abdominal x-ray portrays extensive abnormal gas pattern
at small and large bowel but no dilatation yet other examination tests were inconclusive. His symptoms gradually
resolved and achieve full recovery after discontinued Metformin. Even though, metformin was widely use, the most
common cause of chronic diarrhoea among diabetic patient is still metformin until proven otherwise. Hence, the
necessary precaution should be practice as extent of reaction of metformin adverse drug reaction (ADR) to
gastrointestinal tract vary commonly mild to moderate and rarely severe reaction. The delay of suspicion of metformin�induced enteropathy was significantly impaired his social life, burden with unnecessary invasive investigation and hinder the management of diabetes to achieve good glycaemic control. This case emphasizes on the crucial aspect of assessing drug history and attempt drug free-interval if suspicion of adverse drug reaction. |
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